|
KMID : 0613820220320020155
|
|
Journal of Life Science
2022 Volume.32 No. 2 p.155 ~ p.160
|
|
|
Evaluation of Antithrombosis and Antioxidant Activities of the Ethanol Extract of Different Parts of Hibiscus cannabinus L. cv. ‘Jangdae’
|
|
Kang Deok-Gyeong
Lee Yun-Jin
Kim Young-Min
Sohn Ho-Yong
|
|
|
Abstract
|
|
|
|
Kenaf (Hibiscus cannabinus L.), one of the four major fiber crops, is attracting attention for its efficient CO2-absorbing ability and versatility for producing daily supplies, including textiles. In Korea, a new cultivar ‘Jangdae’ was established in 2013. The ease of cultivation and seed gathering of ‘Jangdae’ has led to its nationwide cultivation. However, evaluation of the bioactivities of the different parts of kenaf, and especially the ‘Jangdae’ cultivar, remains rudimentary. In this study, the antithrombosis and antioxidant activities of extracts prepared from different parts of the ‘Jangdae’ cultivar were evaluated by determining their effects on blood clot formation. Extracts prepared from seeds (HC-SD), seedpods (HC-SP), leaves (HC-L), stems (HC-S), and roots (HC-R) of the ‘Jangdae’ cultivar strongly inhibited blood clot formation. In particular, the HC-SD, HC-SP, and HC-S extracts showed strong inhibition against the coagulation factors prothrombin, and thrombin. The HC-SP extract showed strong antioxidant activities, such as scavenging ability against DPPH anion, ABTS cation, nitrite, and reducing power. Since blood clot formation is closely related to oxidative stress, the HC-SP extract could be developed as a novel anticoagulation and antioxidant resource. This is the first report of the antithrombosis activities of different parts of H. cannabinus L. cv. ‘Jangdae’.
|
|
|
KEYWORD
|
|
|
Anti-oxidant, anti-thrombosis, Hibiscus cannabinus L., ‘Jangdae’ cultivar
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|